NAD+· 500mg
Nicotinamide adenine dinucleotide. The redox currency of every cell.
Individual
$64.80
label.overview
Direct NAD+ injection. Bypasses the salvage pathway and elevates plasma NAD+ within minutes.
NAD+ is the obligate cofactor for sirtuins, PARPs, and the electron-transport chain. Cellular NAD+ falls roughly 50% between age 20 and 60.
Mechanism
Direct NAD+ substrate; sirtuin and PARP activation.
Researcher notes
- • 50 mg subcutaneous, once daily, 5 days per week (2 days off).
- • Slow push; many protocols dilute each dose with 0.5–1 mL sterile saline to soften the SC sting.
- • Rotate injection sites to minimize local irritation.
Mechanism
Direct NAD+ substrate; sirtuin and PARP activation.
Half-life
Plasma minutes; tissue 24–72 hours
Reconstitution
Add 5 mL bacteriostatic water to the 500 mg vial. Each 1 mL = 100 mg.
Storage
Lyophilized: 2–8 °C, protect from light. Reconstituted: 2–8 °C, use within 14 days.
Reconstitution & general research dosing
- Reconstitution
- 5 mL bacteriostatic water into a 500 mg vial → 100 mg/mL (each 0.5 mL = 50 mg). Many research protocols dilute the SC dose further with sterile saline to soften injection-site sting.
- Typical research dose
- Commonly referenced at 50 mg per administration, subcutaneous.
- Frequency
- Once daily, 5 days per week (2 days off).
- Vial duration
- A 500 mg vial covers 10 dosing days at 50 mg/day (= 250 mg/week, 5 days on / 2 off) — finishing inside the 14-day reconstituted-use window with no waste.
- Storage
- Refrigerate 2–8 °C; use within 14 days reconstituted. Protect from light.
- Inject slowly — rapid push is widely reported as the main cause of SC sting.
- Many protocols pre-dilute each 0.5 mL dose with 0.5–1 mL of sterile saline to soften the injection.
- Rotate subcutaneous sites to limit local irritation.